Carboxylic acids and derivatives
Medchemexpress LLC VH 101, acid | 2408341-97-7 | 98.8% | C28H35FN4O6S | 25 MG
VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. It contains an E3 ligase ligand plus an alkyl linker with a terminal amine, making it ready for conjugation to a target protein ligand.
- Functionalized von-Hippel-Lindau (VHL) protein ligand
- For PROTAC research and development
- Contains an E3 ligase ligand
- Alkyl linker with terminal amine for conjugation
- VHL protein is a substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes
- Used by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein
Apexbio Technology LLC PKUMDL-LC-101-D04 2143896-83-5 1mg
PKUMDL-LC-101-D04 (CAS 2143896-83-5) is a small molecule allosteric activator of glutathione peroxidase 4 (GPX4) a key enzyme regulating ferroptosis In biochemical and cell extract assays PKUMDL-LC-101-D04 enhances GPX4 activity to 150% of baseline at concentrations of 20 M and 61 M respectively This compound serves as a valuable tool for investigating the modulation of ferroptosis through GPX4 activation and supports research into oxidative stress and cell death mechanisms
Selleck Chemical LLC MZ-101-E1913-25MG
MZ-101 (GYS1-IN-2) is a potent small molecule inhibitor of Glycogen synthase 1(GYS1) with an IC50 value of 0 041 M By depleting muscle glycogen MZ-101 treatment normalizes glycogen levels and corrects transcriptional and metabolic abnormalities in Pompe mice
Medchemexpress LLC UCPH-101 | 1118460-77-7 | 98.6% | 422.48 | 25 MG
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. It is for research use only.
- Inhibits EAAT1 anion currents in a concentration-dependent manner
- Suitable for research applications
Medchemexpress LLC PKUMDL-LC-101-D04 1g | 2143896-83-5 | 378.94 | C14H23ClN4O2S2 | 1 G
PKUMDL-LC-101-D04 is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) supplied as a hydrochloride research chemical. It increases GPX4 enzymatic activity (reported pEC50 = 4.7) and has been used in cell and animal studies to inhibit ferroptosis and reduce inflammation. Molecular formula C14H23ClN4O2S2; molecular weight 378.94 Da.
- Allosteric activator of glutathione peroxidase 4 (GPX4).
- Reported activity pEC50 = 4.7 in biochemical assays.
- Hydrochloride salt form for improved stability and handling.
- Molecular formula C14H23ClN4O2S2, molecular weight 378.94 Da.
- Provided as a research reagent; not for human use.
- Typical pack size: 1 g.
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 1 G
Sodium lauroyl glutamate is an anionic amino acid surfactant used primarily in cleaning products. It is considered a mild surfactant with low irritation to nude mouse skin, exhibiting a pH value of 5.41. It also has potential for irritant contact dermatitis and possible anti-irritating effects in surfactant mixtures on human skin.
- Anionic amino acid surfactant
- Mild surfactant properties
- Ideal for cleaning product formulations
- Low irritation potential
- pH value of 5.41
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.1% | 25 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment (excitation/emission: 411 nm/512 nm) that exhibits solid-state fluorescence and is available as a commercial colorant. It is suitable for laboratory centrifugation and storage.
- Excitation/emission: 411 nm/512 nm
- Exhibits solid-state fluorescence
- For research use only
![Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238871.png-250.jpg)
Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG
MAL3-101 is a small-molecule allosteric inhibitor of heat shock protein 70 (HSP70) used in cellular and biochemical research. It inhibits HSP70 ATPase activity by blocking interaction with Hsp40 co-chaperones, perturbing protein folding and proteostasis pathways. The compound is supplied as a high-purity research reagent (CAS 831217-40-4) and is intended for in vitro and preclinical studies only.
- Allosteric inhibitor of HSP70 ATPase activity.
- Blocks Hsp40-Hsp70 interaction to disrupt protein folding.
- Applicable to cellular models studying proteostasis and cancer biology.
- High reported purity supports reproducible results.
- Supplied in small quantities suitable for screening and pilot studies.
- For research use only; not for human or veterinary use.
Medchemexpress LLC MZ-101 (GYS1-IN-2) | 2839908-40-4 | 99.0% | 449.52 | C25H28FN5O2 | 10 MG
MZ-101 (GYS1-IN-2) is an orally active, potent, and selective small-molecule inhibitor of glycogen synthase 1 (GYS1) with an IC50 of 0.041 μM. It reduces glycogen concentrations in cells and in mice and is used to study GYS1-mediated Pompe disease and other glycogen storage disorders.
- Potent, selective GYS1 inhibition (IC50 = 0.041 μM).
- Reduces glycogen concentrations in cells and animal models.
- Orally active small molecule suitable for in vivo studies.
- High purity (98.98%) and solid physical form for storage stability.
- Available in small solid quantities and DMSO solutions for flexible dosing.
- Storage: powder stable at -20 °C (up to three years) and 4 °C (up to two years).
Medchemexpress LLC BNC-101 10mg | 10mg
BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
Medchemexpress LLC UK-101 | 1000313-40-5 | 99.6% | 484.74 g/mol | 50 MG
UK-101 is a potent, selective inhibitor of the immunoproteasome β1i (LMP2) subunit, commonly used in proteasome biology and cancer research to study apoptosis and proteasome-mediated pathways.
- Potent LMP2 inhibition with an IC50 of about 104 nM.
- Demonstrates high selectivity versus related proteasome subunits for target-specific studies.
- Induces cell apoptosis, useful in cancer biology assays.
- High purity (≈99.6%) for reproducible experimental results.
- Soluble in DMSO (≈7.3 mg/mL) for easy stock preparation.
- Stable as a powder under low-temperature storage for long-term use.
- Provided in a small research pack suitable for laboratory assays.
TARGETMOL CHEMICALS INC MG-101 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. purity: 98%
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.1% | 100 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment that exhibits solid-state fluorescence and is available as a commercial colorant.
- Exhibits solid-state fluorescence
- Available as a commercial colorant
- Yellow bis-azomethine pigment
- Excitation/emission: 411 nm/512 nm
AdipoGen Sulforhodamine 101 acid Cl
Chemical. CAS 82354-19-6. Formula C31H29ClN2O6S2. MW 625.15. Synthetic. Sulforhodamine 101 sulfonyl chloride also called Texas Red sulfonyl chloride is a popular long wavelength amine-reactive rhodamine dye. Because the dye is quite unstable in water, reactions with amines in an aqueous solution must be carried out at low temperature over ice or at 4°C and usually at pH 8.5.
Medchemexpress LLC AVN-101 hydrochlorid 5mg | 1061354-48-0 | 340.89 g/mol | C21H25ClN2 | 5 MG
AVN-101 hydrochloride is a brain-penetrant, orally active 5-HT7 receptor antagonist used in pharmacological research. Supplied as a 5 mg powder with high purity, it is suitable for in vitro assays and preclinical studies requiring selective serotonergic modulation.
- High purity suitable for research applications.
- Brain-penetrant profile for central nervous system studies.
- Orally active salt form compatible with dosing studies.
- Stable powder for sealed, low-temperature storage.
- Small packaging appropriate for early-stage research.